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Bench-top Screening of Wet Clutch Materials with the UMT Tribolab

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In this webinar, we cover the motivation and method of a bench-top screening test for the friction characteristics of wet clutch materials and automatic transmission fluids (ATFs).

A critical characteristic in clutch material friction behaviour is a flat or positive gradient of friction coefficient with increasing velocity. A negative gradient promotes stick-slip behavior, which can lead to undesirable clutch performance characteristics, such as shudder and judder. In this webinar, we cover the motivation and method of a bench-top screening test for the friction characteristics of clutch materials and automatic transmission fluids (ATFs). Such testing is key to the decrease in development time via the ranking of clutch materials and fluids prior to selection for standardized full-scale component test rigs or in-service vehicle field testing. Screening tests are conducted using industry-relevant test conditions, similar to those from the SAE #2 friction test machine, or per the JASCO M348-2012 test standard, including contact pressures, sliding velocities and temperatures. At the conclusion, we present results from bench-top screening tests of paper-based clutch materials which rank materials in the same manner they are ranked when full-scale clutches were tested.

Presenters:


Daniel Soares
Tribology Product Specialist

 


Dr Udo Volz
Application Scientist

AI can enhance MRI-guided radiation therapy plans

© AuntMinnie.com

Artificial intelligence (AI) algorithms can rapidly predict 3D dose distributions for online adaptive MRI-guided radiation therapy plans, enabling swift optimization and quality assessment of these treatments, according to research published in the Journal of Applied Clinical Medical Physics.

Using only contouring information, artificial neural networks (ANNs) developed by researchers from Washington University in St. Louis produced strong performance for predicting 3D dose distributions for treatment plans. What’s more, they also clearly identified about 10% of abdominal cancer treatment plans in the study as inferior and requiring further optimization and refinement, according to the team.

“The prediction models will be useful to improve adaptive planning strategies and workflows through more informed plan optimization and evaluation in real time,” wrote the authors, led by first author M Allan Thomas.

Planned versus predicted dose

The researchers trained and validated the models using a dataset of 310 treatment plans from 53 abdominal cancer patients who had been treated with online adaptive, linac-based MRI-guided radiation therapy. Specifically, the ANN models were designed to predict 3D dose distributions based on the average of prior treatment plans.

“Our models allow a direct, 3D dose comparison between the history of previously treated plans and upcoming plans for future patients without needing to take the time and effort to create an actual treatment plan,” the authors wrote. “This is possible because our models are based on inputs that require only target and [organs-at-risk] structure data, not planned beam parameters.”

The researchers noted that clinical integration of the models requires minimal effort. After retrospectively replanning several of the 25 plans identified by the ANN as inferior in its analysis, the researchers also found that the new plans were closer to the quality level predicted by the model.

“Generally, from 40% to 100% of the difference between the predicted plan metrics and the original values were recovered after replanning,” they wrote. “These results help to further showcase the clinical relevance and utility of the dose prediction models.”

In the future, these 3D dose distribution predictions could be utilized as an alternative input to the current development process for treatment plans, according to the researchers.

“An estimated 3D dose prediction tailored to the specific anatomy of the day could provide a much-improved starting point for subsequent adapted plan development and optimization each fraction,” the authors wrote. “The fact that our ANN models can provide a 3D dose prediction using contour information alone (a fully developed treatment plan is not needed) helps to bolster their potential use as novel inputs for alternative treatment planning strategies.”

As the number of patients treated with online adaptive MR-guided radiation therapy increases and more training data becomes available, it may also be possible to develop improved prediction models based on convolutional neural networks, according to the researchers.

  • This article was originally published on AuntMinnie.com. ©2020 by AuntMinnie.com. Any copying, republication or redistribution of AuntMinnie.com content is expressly prohibited without the prior written consent of AuntMinnie.com.

COVID-19 symptoms detected from a safe distance using infrared light and microwaves

A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. The team’s “access checker” combines infrared and microwave measurements and is already being tested at a Stuttgart hospital. The researchers believe that their system will become an important tool for ensuring the safety of healthcare workers, patients and hospital visitors.

To slow the spread of COVID-19, it is crucial for hospitals to enforce strict yet efficient entrance controls for staff and visitors. To carry out these tests, however, workers must come into regular contact with potentially infected people, putting both parties at risk. As a result, staff controlling access to hospitals must wear personal protection equipment, which is cumbersome and currently in short supply in some places. To address these issues, Schneider’s team created a device that uses a combination of measurements to detect some symptoms of the disease remotely.

One part of the access checker scans a person’s body temperature by measuring infrared radiation emitted by their skin. This is done to detect fever, which is a symptom of COVID-19. The device also checks for increased heart and breathing rates associated with the disease. This is done using a micro-Doppler radar system that bounces microwaves off the subject to detect body motions associated with breathing and blood flow. A similar technique is used by radar guns to measure the speed of vehicles.

Safe distance

Since the device can be operated remotely using a laptop, it allows healthcare workers to maintain a safe distance of more than 2 m from their subjects. Therefore operators do not have to wear personal protection equipment.

Schneider’s team have built a prototype of their remote access checker, which is currently undergoing its first trial run at the main entrance to the Robert Bosch Hospital in Stuttgart. Tests have already shown that the scans can be carried out just as fast as conventional tests for COVID-19 symptoms.

Several hospitals in the surrounding area have already expressed interest in the system and Schneider’s team have now drawn up ambitious plans to build four more monitors to serve them within just two weeks. Ultimately, the team hopes that their work could provide a critical tool for governments and healthcare workers as they fight to contain the spread of COVID-19. Schneider also believes that the technology has applications beyond COVID-19 scanning and could be used for routine screening in locations such as care homes and airports.

Topological effect creates unidirectional photonic device

A photonic device that radiates light only in one direction has been created by researchers in China and the US. Chao Peng, Marin Soljačić and colleagues at Peking University, the Massachusetts Institute of Technology and the University of Pennsylvania created their device by carefully tailoring the shape of a set of etched silica bars – thereby using topology to modify a curious effect that was predicted 90 years ago. The optical device could have multiple applications in optoelectronics.

A key challenge in creating optical circuits is that light will happily travel in both directions through optical devices – which causes unwanted effects. Current solutions such integrating a mirror to reflect light travelling in the wrong direction tend to be bulky, inefficient or difficult to fabricate. Now, researchers in China and the US have put a topological twist on an effect first proposed in 1929 and created a photonic crystal that rediates light in only one direction.

In 1929, John von Neumann and Eugene Wigner discovered that some solutions of the Schrödinger equation for an electron in a potential well involved bound states that nevertheless had enough energy to escape the well. Creating experimental systems that exhibit these “bound states in the continuum” (BICs) was not possible at the time so they remained a mathematical curiosity for several decades. Beginning in the 1970s, researchers realized that the same physics applied beyond quantum mechanics and more broadly to systems of waves. Since then, BICs have been observed in light, sound and water waves as well as surface waves in graphene.

A perfect mirror

In 2013, a team led by Soljačić used BICs to produce a new type of perfect mirror that could trap and reflect light without ever absorbing it. In 2017, Boubacar Kanté at the University of California, San Diego and colleagues extended the concept from controlling the trapping of light to tailoring its emission. They produced an optical “supercavity” from a square lattice structure of indium gallium arsenide phosphide. When pumped at optical frequencies, their structure supported a standing wave at around 1550 nm (the wavelength most commonly used in telecommunications). This was used to create a very narrow linewidth laser that could prove useful in optoelectronics.  However, the emission is spatially symmetric: just as many photons are radiated downwards from the lattice as upwards.

In the latest research research, Soljačić and colleagues in the US and China developed a neat trick to produce an device that sends radiation in only one direction. The team fabricated a periodic array of 500 nm deep and 200 nm wide silicon bars approximately 1 micron apart on a silica substrate. If the bars had been created perpendicular to the substrate, simulations suggested the system would behave as a BIC when excited with 1550 nm light. Instead, however, the researchers tilted the bars slightly, disrupting the BIC and allowing radiation to leak out.

Topological considerations meant that radiation radiated upwards had to have the opposite polarization to radiation emitted downwards. When the bars had been tilted far enough, any radiation radiated downwards would have to be both left-circularly-polarized and right-circularly-polarized at the same time. As no radiation could ever satisfy this constraint, radiation should not be emitted downwards – and least for a perfectly constructed device. The actual device sent thousands of times more optical power upwards than downwards.

“Beautiful work”

Soljačić and colleagues were unavailable for comment, but Kanté – now at the University of California, Berkeley – describes the research as “beautiful work”. “This is probably the highest contrast I have ever seen in a passive structure,” he says. “Normally the ratio is one to two, three or four.” He believes the most interesting aspect is the underlying theory the researchers use to break spatial symmetry and show how radiation can be cancelled in one direction.

He adds a note of caution, however: “Unidirectional does not mean non-reciprocal: even if it only sends signals out in one direction it will still receive them [from both directions],” he says. “To avoid interference this antenna would still require an isolator.” This could have its own advantages, however: “Sometimes you want to be able to couple light efficiently into an optoelectronic chip or back out of it using something called a grating coupler,” he explains. “It could be very useful for that.”

The research described in Nature.

Got the lockdown blues? Take this trivia quiz on astronomy and space

1 What is another name for Tardigrades – the tiny creatures left on the Moon when Israel’s Beresheet craft crashed into the lunar surface in 2019? A Water bears B Water dragons C Water flies D Water horses

2 What object left on the Moon by Apollo astronauts do some scientists think should be retrieved by a future lunar mission? A Alan Shepard’s golf ball B Buzz Aldrin’s bag of faeces C Harrison Schmitt’s rock hammer D Gene Cernan’s lunar rover

3 Who or what were Harriot, Wangshu, Abol and Umbäässa? A Comets B Exoplanets C Craters on Mars D Presidents of the International Astronomical Union

4 What name was given to the two ultra-high energy neutrinos detected in 2014 by the IceCube observatory at the South Pole? A Bill and Ben B Bert and Ernie C Tom and Jerry D Batman and Robin

5 How many of the astronauts on the Apollo 11 mission were quarantined when they returned to Earth? A None B One C Two D Three

6 What topping featured on a Pizza Hut pizza delivered to the International Space Station in 2001? A Anchovies B Mushrooms C Pepperoni D Salami

7 What was the error in the size of the perimeter of the primary mirror on the Hubble Space Telescope after launch in 1990? A 2.2 nanometres B 2.2 microns C 2.2 millimetres D 2.2 centimetres

8 What society did astronomers Mary Blagg, Ella Church, Grace Cook and Fiammetta Wilson become the first female elected fellows of in 1916? A Royal Society B American Astronomical Society C Royal Astronomical Society D Astronomical Society of the Pacific

9 What did NASA recently name its Mars rover to? A Persistance B Perserverance C Persuasion D Perscipacity

10 What kind of lettuce was recently grown on the International Space Station? A Iceberg B Red romaine C Lollo rosso D Frisée

Want to know the answers? We’ll reveal all next week on Friday 1 May.

Update: Answers below the sponsor’s message.

UHV Design logo

Sponsored by UHV Design Ltd, specialists in the design, manufacture and supply of high-quality, low-maintenance, manipulation and heating solutions for thin film deposition, surface-analysis instrumentation and particle-accelerator diagnostics. Visit uhvdesign.com to learn more.

Answers: 1 A    2 B    3 B    4 B   5 D    6 C    7 B   8 C   9 B   10 B

Get Precise Tribology Data Through Surface Profilometry

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This webinar provides an overview of how advanced optical profilometry can contribute to successful tribology tests, and allows one to extract critical data such as wear rate, life time, time to failure and volume removal rates. First, white light interferometry based optical profiling will be introduced. Next, we will present how this method can be applied across a wide range of tribological tests from micron-indentations to high-speed reciprocating tests via scratching and pin-on-disk approaches.  A live practical session will conclude this webinar.

Presenters:


Dr Samuel Lesko
Senior Application Development Manager

Dr Michel Fajfrowski
Application Manager

Combining Atomic Force Microscopy with Optical Techniques

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This webinar will focus on how AFM can be integrated into optical techniques. You will learn concepts from basic sample observation up to single molecule advanced super-resolution inverted optical microscopy simultaneous to AFM. The webinar will also elucidate how tip-enhancement techniques can provide more comprehensive data sets. We will also focus on how high-NA upright optical techniques can be used with AFM on opaque samples or substrates.

Presenters:
Dr Florien Kumpfe
JPK BioAFM Application Scientist

 


Carmen Pettersson
Senior Manager Product Marketing Manager

NanoDMA III for Polymers: Primer and Applications

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This webinar will start with some basic nanoindentation theory and focus on its shortcomings with regards to the unique mechanical characteristics of polymers, particularly their strong time-dependence. To overcome this shortcoming, a nanoscale compliment of Dynamic Mechanical Analysis, Bruker’s nanoDMA III presented. This simple method measures both storage (E’) and loss (E’’) modulus of polymeric materials in a meaningful way.

Having the basics in hand, the nanoDMA III technique can then be applied to increasingly difficult (and often more rewarding) measurements:
• Combining effects of time and temperature for something easy; a thermoplastic, then something more difficult; a liquid silicone.
• Advantages of small-scale testing of bulk polymers over a wide variation in humidity conditions.
• Measuring temperature effects on adhesion, E’ & E’’, and uniformity of coating for pressure sensitive adhesives.

Presenters:

Dr Douglas Stauffer
Senior Manager NI Applications


Dr Rhys Jones
Nanoindentation Product Sales Specialis

Hubble’s best shots: eXtreme Deep Field

Thanks to the finite speed of light, the deeper we look into space, the further back in time we go. But how far back can we see? Hubble’s eXtreme Deep Field answers that question with our deepest-ever view of the universe: some of those faint patches of light in it are galaxies dating back more than 13.2 billion years.

This window into the past gives cosmologists insight into how the earliest galaxies – more than 5000 of which fill the view in this tiny patch of sky – grew as they emerge from a truly ancient era known as the Dark Ages. But the galaxies of the era visible in this image are already a few hundred million years old. To witness the birth of the very first stars and galaxies, we will need a telescope beyond even the capabilities of Hubble.

Fortunately, we should have one soon: the long-delayed James Webb Space Telescope (JWST), currently scheduled for launch in 2021. Designed to observe the universe at infrared wavelengths, it won’t be a true successor to Hubble, but it should prove just as profound in advancing our knowledge of the cosmos as Hubble has been – and continues to be.

Stereotactic ablative radiation to metastases slows prostate cancer progression

Stereotactic ablative radiotherapy

Stereotactic ablative radiotherapy (SABR) is a popular method for treating small, inoperable tumours in various anatomical sites. This type of radiotherapy delivers highly focused, intense radiation doses in few treatment sessions, which increases the radiation’s cell-killing effectiveness. A phase II study conducted by researchers from the Johns Hopkins Sidney Kimmel Cancer Center has now shown that SABR can slow disease progression in prostate cancer patients with up to three metastases (JAMA Oncol. 10.1001/jamaoncol.2020.0147).

Prostate cancer is the second most common cancer in men worldwide and the most common in the USA and many European countries. Once the tumour has metastasized, the disease is incurable, though treatment options exist that can slow its progression. One standard treatment for men with hormone-sensitive metastatic prostate cancer is a type of hormone therapy called androgen deprivation therapy (ADT). However, ADT can have side effects such as impotence or loss of bone and muscle density. Many men therefore prefer to delay this treatment for as long as possible.

SABR as an alternative to early hormone therapy

Recently, SABR has been gaining interest as a treatment option for cancers in the early metastatic (oligometastatic) stage, where patients have few, localized metastases. The results of the ORIOLE (Observation versus Stereotactic Ablative Radiotherapy for Oligometastatic Prostate Cancer) phase II randomized controlled trial suggest that treating prostate cancer oligometastases with SABR early on could be a strategy to delay the need for ADT and its harsh side effects.

The trial included 54 men with recurrent hormone-sensitive prostate cancer, and between one and three metastases, who were randomized to receive either SABR or observation only.

Ryan Phillips and Phuoc Tran

The researchers, led by Phuoc Tran of the Johns Hopkins University School of Medicine, report that of 36 patients treated with SABR only, seven (19%) suffered disease progression after six months, while 11 of 18 (61%) in the observation-only group did. Tran and colleagues further report no severe side effects in the SABR trial arm and no significant difference in patient-reported quality-of-life when compared with the observation-only arm.

Triggering the immune system

In addition to showing SABR’s safety and effectiveness for treating these patients, the ORIOLE trial results also hint at an underlying mechanism. The researchers detected an expanded population of T cells in the blood of patients treated with SABR compared with observation-only patients. This suggests that the treatment may have stimulated a body-wide immune response towards the tumours.

“It has been a longstanding question, especially important now in the era of immunotherapy, whether any type of radiation, and SABR specifically, can stimulate the immune system,” Tran said in a recent press release. “Our trial offers the best data to date to suggest that SABR can cause a systemic immune response.”

Finally, the team found that the patients could be divided into low-risk and high-risk groups based on specific tumour gene mutations. They found that SABR was especially effective at slowing disease progression in the low-risk group, indicating that tumour DNA mutation profiles might predict how well a patient responds to SABR.

While these results point to exciting possibilities for new combined treatments and patient risk stratification, Tran and colleagues caution that further studies are needed to validate these insights. Currently, the team is focusing its efforts on further investigating disease-slowing treatments for metastatic cancers. For example, in an ongoing trial called RAVENS, they examine the effect of combining SABR with radium-223 to combat bone metastases.

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