Optimizing the cryopreservation of cells
Freezing of cell-laden hydrogels is optimized using a panel of cryoprotectants
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Geoffrey Potjewyd is a PhD student contributor to Physics World, working in the Division of Neuroscience and Experimental Psychology as part of the CDT in regenerative medicine at the University of Manchester. He is studying the neurovascular unit in relation to vascular dementia and Alzheimer's disease, using biofabrication, biomaterials and stem-cell-based techniques.
Freezing of cell-laden hydrogels is optimized using a panel of cryoprotectants
Bioprinting blended biomaterials allow for both drop-on-demand 3D-printing and blood vessel formation
A biofabricated microfluidic chip images tumour cell invasion of the extracellular matrix
A microfluidic blood–brain barrier platform separates media flow for different cell compartments but allows for interface interaction
Non-invasive imaging technique correlates small vessel disease progression to cognitive decline
Optimizing the physical properties and mechanical parameters of the extracellular matrix boosts the functionality of vascular cells
3D-printed blood vessels reproduce patient clots. Blood clots in an artery – otherwise referred to as an arterial thrombosis – are potentially fatal, and are a major risk factor leading to strokes and heart attacks
Biomaterial-free 3D bioprinting opens the door to bespoke, non-immunogenic 3D tissue constructs for transplantation and grafting
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